Trivia

Hard

Alcohol Is An Antidote To Poisoning By What?

Bleach
Rattlesnake Venom
Strychnine
Antifreeze

Answer: Antifreeze

Ethylene glycol is the primary ingredient in automotive antifreeze and a cause of accidental poisoning in children and household pets due to its sweet taste. The source of the toxicity isn’t necessarily the compound itself, but the metabolites thereof. In the body, ethylene glycol starts off by producing neurological and gastrointestinal symptoms (similar to alcohol poisoning), but then shifts to problems such as hyperventilation, metabolic acidosis, cardiovascular dysfunction, and eventual kidney failure as it is broken down into glycolic and oxalic acids.

Fortunately, if the patient is treated quickly enough treatment is usually successful and the patient almost always makes a full recovery. The two primary treatments used in ethylene glycol poisoning cases are fomepizole and ethanol (as in grain alcohol). Both treatments work on the same principle: both compounds compete with the ethylene glycol for alcohol dehydrogenase (an enzyme required for the metabolization of ethylene glycol and ethanol). Because ethanol has a higher affinity for the enzyme than ethylene glycol (by a magnitude of roughly 100 times), the ethanol quickly binds with all the available enzyme and the ethylene glycol is blocked from breaking down into glycoaldehyde, which prevents further degradation into highly toxic glycolic acid and oxalic acid.

Trivia

Hard

Which Of These National Historic Landmarks Is Dedicated To Thomas Jefferson?

Trivia

Easy

The Opposite Of Albinism Is Called?

Trivia

Hard

What Is An Olympic Gold Medal Primarily Composed Of?

Trivia

Hard

What Space Mission Was The First To Visit Two Planets?

Trivia

Hard

The Fear Of Halloween Is Known As?

Trivia

Hard

What Was The First Video Game Played In Space?

Trivia

Hard

8-Track Music Players Were Originally Invented For Use In What?

Trivia

Hard

The Oldest Genetic Proof Of Malaria Was Found In A?

Trivia

Hard

Many Spaghetti Spoons Have A Large Hole In The Center For?

Trivia

Hard

The Large Protrusion That Hangs Off A Turkey’s Forehead Is Called A?